Internationally, a lot of [Bioinformatics] OpenSource project are in progress. OpenSource project is powerful development method.

• [OBF]'s projects

• [EMBOSS] : BiologicalSequenceAnalysis tool development (in [Unix], [Cee] or CeePlusPlus)

• [Ensembl] : Human [Genome] annotation system development

• PyMol

• BioLisp

• BioMoby

• [GFF]
• [GMOD]
• [MGED]
• [OBDA]

• BioinformaticsDotOrg

• OpenInformaticsDotOrg

and a lot of [Bioinformatics] OpenSource project are maintained in SourceForge. You can participate these projects.